|Intrommune Therapeutics Publishes Peanut Allergy and Immunotherapy Report|
|By GLOBE NEWSWIRE|
|Tuesday, 23 February 2021 07:00|
NEW YORK, Feb. 23, 2021 (GLOBE NEWSWIRE)
NEW YORK, Feb. 23, 2021 (GLOBE NEWSWIRE) -- Intrommune Therapeutics, a New York-based clinical stage biotechnology company developing a patient-friendly immunotherapy platform for the treatment of peanut and other food allergies, partnered with The Solution Lab (“TSL”) to publish the “Peanut Allergy and Immunotherapy – Treatment Landscape & Future Outlook” white paper.
“We are committed to improving the lives of patients suffering from peanut allergies,” said Michael Nelson, CEO, Intrommune Therapeutics. “We are excited to publish this white paper and hope it contributes to greater understanding of peanut allergy and the emerging role of immunotherapy for peanut allergy sufferers.”
Peanut allergy is an ever-increasing social, clinical, and financial burden for society in developed countries. Due to the lack of treatments, avoidance continues to be the standard of care, resulting in economic and emotional burden for patients and caregivers. Peanut allergy concerns have been compounded in the face of the global COVID-19 pandemic.
Allergic reactions to food impact over 30 million people annually in the US.1 With approximately 5.4 million adults and 1.6 million children in the United States suffering from peanut allergy, a type of food allergy,1 the incidence continues to increase rapidly. Traditionally children are taught to avoid the specific food(s) that trigger allergic reactions. Unfortunately, despite avoidance steps, children suffer from frequent allergic reactions and anaphylaxis from food allergies accounts for nearly $760 million in annual direct medical costs in the US.2
“In recent years, immunotherapy has been the focus of peanut allergy treatment research. This therapy reduces the responsiveness of the immune system to specific allergy-triggering foods, thereby decreasing the severity and incidence of allergic reactions,” said Stefanie Mazlish, TSL CEO. “The main modality currently available is oral immunotherapy (OIT), where small, controlled doses of allergy-triggering foods are ingested. Although OIT can be an effective treatment, the ingestion of allergens is linked to a higher risk of adverse events, more severe side effects, and limitations on the patient's lifestyle, especially for children and their parents.”
Researchers are now exploring the utility of oral mucosal immunotherapy (OMIT). An OMIT modality that delivers allergens to a wider area of the oral cavity than other immunotherapies could dramatically increase efficacy. According to this white paper, Intrommune’s OMIT product, INT301, is a toothpaste formulated with peanut allergens, thus emerging as a strong contender to OIT.
“A toothpaste-based modality delivers allergens to the majority of the oral cavity surface area without the risk of significant ingestion of peanut protein,” said William Reisacher, MD, Senior Scientific Advisor, Intrommune Therapeutics. “This optimizes both safety and efficacy, expanding on the successful peanut desensitization proven to occur when liquid peanut protein is repeatedly placed under the tongue, and provides more options for younger children.”
About Oral Mucosal Immunotherapy
About Intrommune Therapeutics
For more information on Intrommune Therapeutics, please visit http://www.intrommune.com
About The Solution Lab
For more information on TSL: The Solution Lab, please visit http://www.thesolutionlab.org
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John F. Kouten