Ligand Signs Multi-Program Captisol® License Agreement with Avion; La Jolla Receives Notice of Allowance for Claims Covering Modified Pectin Print E-mail
By Staff and Wire Reports   
Thursday, 14 August 2014 18:38
Below is a look at some of the headlines for companies that made news in the healthcare sector on August 14, 2014.

Ligand Pharmaceuticals Incorporated (NASDAQ: LGND)
announces the signing of a commercial license agreement with Avion Pharmaceuticals, LLC for the development and commercialization of four Captisol-enabled programs. Under the terms of the agreement, Ligand is entitled to receive an up-front payment, and is eligible to receive revenue from Captisol material sales, potential milestone payments, and royalties on future net sales of the products containing Captisol.

“Through this multi-program partnership with Avion Pharmaceuticals, we are adding a new organization to our growing list of partners and have added four additional fully-funded programs to our existing portfolio of more than 100 Shots-on-Goal,” commented John Higgins, President and Chief Executive Officer of Ligand Pharmaceuticals. “Ligand continues to expand its portfolio of assets to deliver value to shareholders. Importantly, this partnership also demonstrates new demand for Captisol in both oral and topical administration, adding to the position Captisol has established in enabling injectable products.”



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La Jolla Pharmaceutical Company (NASDAQ: LJPC)
, a leader in the development of innovative therapies intended to significantly improve outcomes in patients suffering from life-threatening diseases, announced the United States Patent and Trademark Office (“USPTO”) has issued a notice of allowance for patent application number 14/254,510 covering methods of treating chronic inflammation by intravenous administration of aqueous modified pectin solutions with molecular weights greater than 25 kilodaltons.

“We are pleased to have received these additional claims covering aqueous solutions of modified pectin with limited molecular weight restrictions for the treatment of chronic inflammation,” said James Rolke, Vice President of Research and Development at La Jolla and an inventor on the allowed patent application. “These newly allowed claims expand our proprietary position for the use of modified pectin as a treatment for organ diseases that result from chronic inflammation.”

The Company’s intellectual property portfolio includes several issued and pending patents for the treatment of chronic inflammation. These issued and pending patents provide or will provide proprietary coverage for the Company’s pectin-based drugs, GCS-100 and LJPC-1010, as well as other modified pectin materials, including all modified pectins currently in clinical development.



Also Thursday:



Arno Therapeutics, Inc. (OTCQB:ARNI)
, a clinical stage biopharmaceutical company focused on the development of oncology therapeutics, today announced financial results for the second quarter of 2014 and provided an update on recent clinical developments.

Biocept, Inc. (Nasdaq:BIOC)
, a molecular oncology diagnostics company specializing in Circulating Tumor Cells (CTCs) and Circulating Tumor DNA (ctDNA) biomarker analysis, today provided a business update following the recent filing with the US Securities and Exchange Commission of its Quarterly Report on Form 10-Q for the second quarter ended June 30, 2014.

Capstone Therapeutics (OTCQB:CAPS)
, will hold a conference call and webcast to provide an operating update and announced financial results for the second quarter 2014.

CareDx, Inc. (Nasdaq:CDNA)
, a molecular diagnostics company focused on the development and commercialization of clinically differentiated, high value, non-invasive surveillance solutions for transplant recipients, today announced that it will release its financial results for the second quarter of 2014 after the close of trading on August 27, 2014.

Cellular Biomedicine Group Inc. (Nasdaq:CBMG)
, a biomedicine firm engaged in the development of new treatments for degenerative and cancerous diseases, today reported financial results for the three and six months ended June 30, 2014 and provided business highlights including the six-month data from its Phase I/IIa clinical trial for ReJoinTM treatment for Knee Osteoarthritis (KOA).

Cloud Medical Doctor Software Corporation (OTCQB:NSCT)
is pleased to announce 2014's third quarter revenue increase of 716.81% over last year's third quarter, marking the completion of the transition from development stage to commercial stage for its CipherShop Division.

CollabRx, Inc. (Nasdaq:CLRX)
announces financial results and business highlights for the first quarter of fiscal year 2015, which ended June 30, 2014.

Cytomedix, Inc. (OTCQX:CMXI)
, a pioneer in biodynamic therapies, today reported financial results for the three months ended June 30, 2014.

Endocyte, Inc. (Nasdaq:ECYT)
, a leader in developing targeted small molecule drug conjugates (SMDCs) and companion imaging agents for personalized therapy, today announced that the Company's scientific management team has been selected by the American Chemical Society as the recipient of the 2015 George and Christine Sosnovsky Award for Cancer Research.

EXL (Nasdaq:EXLS)
, a leading business process solutions company, today announced that its health technology group EXL Landa has introduced CareAdvise, a product that seamlessly integrates with the CareRadius suite to deliver evidence-based clinical content.

GreeneStone Healthcare Corporation (OTCBB:GRST)
, a provider of healthcare services including addiction and mental health, has filed its second quarter 10Q and for the first time posted a quarterly profit since becoming a medical company.

ImmuDyne, Inc. (OTCQB:IMMD)
announced today that it has entered into a definitive agreement with the Sedona Institute For Age Management, LLC an affiliate of the Sedona Integrative Medical Clinic, LLC, to complete a clinical study on a new application of the company's patented beta glucan technology.

Medical Marijuana, Inc. (OTC Pink:MJNA)
is pleased to announce that its subsidiary, Wellness Managed Services' MPS International (MPSI), was recently featured by Bloomberg and was selected to provide on-site event security services at Seattle Hempfest August 15-17.

Nuvilex, Inc. (OTCQB:NVLX)
, a clinical-stage, international biotechnology company providing cell and gene therapy solutions for the treatment of diseases, announced today that its partner, Austrianova, has reported the results from the second Phase 2 clinical trial combining the Cell-in-a-Box® cellulose-based live cell encapsulation technology plus low doses of the anticancer prodrug ifosfamide in patients with advanced, inoperable cancer has been published in the scientific journal Pharmaceutics.

Spine Pain Management, Inc. (OTCQB:SPIN)
, a technology-driven, financial services, medical device, and healthcare solution company servicing the multi-billion dollar spine injury sector, today announced financial results for its second quarter 2014.

TearLab Corporation (Nasdaq:TEAR) (TSX:TLB)
announced today that it will host an "Analyst and Investor Day" in San Diego, CA on Tuesday, September 23, 2014.



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