|Sarepta Announces Favorable Safety Results from Phase I Influenza Drug Candidate; BioCryst Declared The NIAID Exercised Two Alternatives For GMP Drug|
|By Marilyn Mullen|
|Thursday, 02 October 2014 19:26|
Sarepta Therapeutics, Inc., (NASDAQ:SRPT) 21.63 -0.25 (-1.14%), declared positive safety results on Tuesday by the separate dose portion of a Phase I study of its lead influenza treatment candidate.
The test of the treatment, called AVI-7100, is being conducted in partnership between the Sarepta Therapeutics and the National Institute of Allergy and Infectious Diseases (NIAID).
The separate dose portion of the Phase I analyze in forty able-bodied volunteers in either live or placebo cohorts. The final result* showed that AVI-7100 was well endured with no clinically important harmful effects. An nonpartisan data and safety supervising board went over the results of the study and urged it carry on as planned.
The treatment employs Sarepta Therapeutics’ PMOplus chemistry, which is also the basis of the company’s clinical-stage Ebola and Marburg drug candidates. Sarepta spokespersons conveyed optimism that additional collaborative work with the NIH and NIAID using PMOplus will bring about additional treatments for dangerous diseases.
“The similar drug-like characteristics demonstrated across a broad spectrum of targets offers a versatility that will be especially critical in developing a capability to rapidly respond and adapt to real-world, global health threats – whether that is an Ebola outbreak, an influenza pandemic, or a never-before-seen emerging infectious disease,” Chris Garabedian, the president and CEO of Sarepta Therapeutics, said.
BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) declared that the National Institute of Allergy and Infectious Diseases (NIAID) has exercised two other alternatives under its contract, which allows for GMP drug substance and drug product manufacture of BCX4430. Exercising these options includes up to a $2.0 million growth to the existing development contract.
At the end of the trading day BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) moved up 3.78% to close at $10.15. BCRX is -30.57% away from its 52 week high and is moving 123.08% ahead of its 52 week low. BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) return on investment (ROI) is -106.20% while return on equity (ROE) is -175.80%.
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