Amarin: Too Many Positives to Ignore |
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By Patrick Crutcher | ||
Thursday, 24 February 2011 03:49 | ||
![]() Remember, Amarin is developing AMR101(ethyl icosapentate), which is an ultra-pure (>96% ethyl-EPA), prescription-grade omega-3 fatty acid compound for the treatment of patients with very high triglyceride(TG) levels(MARINE, 500 ≤ TGL ≤ 2000 mg/dL) and the other for the treatment of patients with high triglycerides with mixed dyslipidemia(ANCHOR , 200 ≤ TGL ≤ 500 mg/dL). The MARINE indication covers more than 3.5-4.0 million patients, while the ANCHOR indication covers well over 30-35 million patients in the US. Both Phase 3 trials are being conducted under Special Protocol Assessment (SPA) agreements with the FDA. Back in November, Amarin demonstrated very positive results in the MARINE study, demonstrating a 33%(4g, high dose) and 20%(2g, low dose) reduction in TG levels, without an effect on cholesterol(something Lovaza actually increases). Recently, Canaccord Genuity reiterated a 'Buy' on Amarin, with an $11 price target. Canaccord had this to say,"Reiterating rating and PT on high chances of ANCHOR success, AMR 101 market potential. AMR101 is AMRN’s purified EPA omega-3 drug for high triglycerides. We expect positive top-line ANCHOR and full MARINE pivotal data in April. We think AMRN may submit the AMR101 NDA for high triglycerides H1/11 with approval in H1/12. Our $11 target is based on a pNPV analysis." Investors should realize that the $11 price target is risk adjusted for the possibility of tepid ANCHOR results. Consider that positive results in the ANCHOR indication alone are potentially worth several(>$2) billion dollars, more than twice their marketcap. They are even talking about additional indications in inflammation, prevention of cardiovascular events and combo therapy with statins. Amarin is widely seen as a likely acquisition target in 2011, especially with positive ANCHOR study results. Back in January at the JP Morgan Healthcare Conference, CEO Joe Zakrzewski, said “I have more companies interested in this asset(AMR-101) than employees,” The company employs 17 people. Be sure to check out the webcast from this conference; Zakrzewski gives a very compelling presentation. We will continue to following Amarin closely as we get closer to ANCHOR results. In addition to everything else, we see a very interesting technical pattern developing on the AMRN chart (see below) which leads us to believe that the stock is coiled up and may be getting ready to continue it's recent uptrend. As you can see, there is a symmetrical triangle- which is often seen or thought of as a continuation pattern developed in markets that are, for the most part, aimless in direction. According to Investopedia, and others, "during this period of indecision, the highs and the lows seem to come together in the point of the triangle with virtually no significant volume. When the investors do figure out which way to take the issue, it heads north or south with big volume in comparison to that of the indecisive days and or weeks leading up to the breakout. Nine times out of ten, the breakout will occur in the direction of the existing trend. But, if you are looking for an entry point following a symmetrical triangle, jump into the fray at the breakout point.
These patterns, both the symmetrical triangles on the bullish as well as the bearish side are known to experience early breakouts that give investors a "head fake". Hold off for a day or two after the breakout and determine whether or not the breakout is for real. Experts tend to look for a one-day closing price above the trendline in a bullish pattern and below the trendline in bearish chart pattern. Remember, look for volume at the breakout and confirm your entry signal with a closing price outside the trendline. ![]() Recent coverage - http://biomedreports.com/2011011862462/amarin-attracts-long-list-of-suitors.html More Amarin information - http://investor.amarincorp.com/releases.cfm Disclosure: Long AMRN ![]() "Featured Content" profiles are meant to provide awareness of these companies to investors in the small-cap and growth equity community and should not in any way come across as a recommendation to buy, sell or hold these securities. BiomedReports is not paid or compensated by newswires to disseminate or report news and developments about publicly traded companies, but may from time to time receive compensation for advertising, data, analytics and investor relation services from various entities and firms. Full disclosures should be read in the 'About Us Section'. Add this page to your favorite Social Bookmarking websites ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |