DURECT Corporation (NASDAQ:DRRX) has confirmed receiving positive results from multi-dose Phase 1 clinical trial with oral formulation of DUR-928. 

James E. Brown, President and CEO of DURECT, opined that after the starting successful single-dose Phase 1 study, the firm has got additional safety data which also has no drug accumulation in the multiple-ascending-dose Phase 1 trial. He added that the healthy volunteers did not witness any serious drug-related adverse events and that it plans to conduct Phase 1 trials during second half of the year with injectable administration of DUR-928.

The Phase 1 was a randomized and placebo-controlled multiple-ascending-dose study for assessing safety, tolerability, and pharmacokinetics of DUR-928 when given orally for 5 days to healthy volunteers. 

DUR-928 was well-tolerated at both dose levels and patients did witness any significant changes in vital signs, laboratory values or ECG parameters. On the other hand, Peak plasma concentrations achieved were about 100-fold higher than endogenous levels and no accumulation was there in repeat dosing in plasma concentrations.

Shares of the company are reversing early gains and now down 2.55% to $2.29. Earlier in the session, the stock was up as much as 11.50% to $2.59.

"Featured Content" profiles are meant to provide awareness of these companies to investors in the small-cap and growth equity community and should not in any way come across as a recommendation to buy, sell or hold these securities. BiomedReports is not paid or compensated by newswires to disseminate or report news and developments about publicly traded companies, but may from time to time receive compensation for advertising, data, analytics and investor relation services from various entities and firms. Full disclosures should be read in the 'About Us Section'.

---

Add this page to your favorite Social Bookmarking websites